Does Helicobacter pylori eradication therapy result in a platelet count improvement in adults with immune thrombocytopenic purpura regardless of H pylori infection? ASH evidence-based review 2008.

HP-positive HP-negative HP-positive nonHP-negative nonDefinition of Country responders responders responders responders response of origin Morimoto 20072 7 12 0 3 Platelet count increase by 20 or more Japan above baseline Asahi 20063 16 26 0 11 Increase in platelet count by 100 or more Japan by 24 weeks Inaba 20054 11 25 0 10 Platelet count above 100 Japan Takahashi 20045 8 15 0 5 Platelet count increase by 20 or more Japan above baseline Michel 20046 1 15 0 10 Platelet count at least 50 and double USA from baseline Ando 20047 10 17 0 2 Platelet count above 90 Japan Hino 20038 12 21 0 3 Significant increase in platelet count Japan